A wet wipe, also known as a wet towel or a moist towelette, disposable wipe, disinfecting wipe, or a baby wipe (in specific circumstances) is a small to medium-sized moistened piece of plastic or cloth that either comes folded and individually wrapped for convenience or, in the case of dispensers, as a large roll with individual wipes that can be torn off. Wet wipes are used for cleaning purposes like personal hygiene and household cleaning; each is a separate product depending on the chemicals added and medical or office cleaning wipes are not intended for skin hygiene.

In 2013, owing to increasing sales of the product in affluent countries, Consumer Reports reported that efforts to make the wipes "flushable" down the toilet had not entirely succeeded, according to their test.